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Remodelin

CAS No. 949912-58-7

Remodelin ( —— )

Catalog No. M16792 CAS No. 949912-58-7

A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 In Stock
10MG 63 In Stock
25MG 119 In Stock
50MG 176 In Stock
100MG 259 In Stock
200MG 390 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Remodelin
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
  • Description
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    NAT10inhibitor
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    949912-58-7
  • Formula Weight
    282.36
  • Molecular Formula
    C15H14N4S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1
  • Chemical Name
    Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Larrieu D, et al. Science. 2014 May 2;344(6183):527-32.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
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