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Remodelin

CAS No. 949912-58-7

Remodelin ( —— )

Catalog No. M16792 CAS No. 949912-58-7

A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 45 In Stock
10MG 63 In Stock
25MG 119 In Stock
50MG 176 In Stock
100MG 259 In Stock
200MG 390 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Remodelin
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
  • Description
    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules; significantly reduces the prevalence of misshapen nuclei in HGPS cells, prevents FTI-induced nuclear shape defects in normal fibroblasts and U2OS cells; does not affect Golgi apparatus integrity or tubulin polymer assembly, and does not cause cells to accumulate in mitosis.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    NAT10inhibitor
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    949912-58-7
  • Formula Weight
    282.36
  • Molecular Formula
    C15H14N4S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1
  • Chemical Name
    Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Larrieu D, et al. Science. 2014 May 2;344(6183):527-32.
2. Mathieu J, et al. Cell Stem Cell. 2016 Jul 7;19(1):3-4.
3. Cobb AM, et al. Aging Cell. 2016 Jul 27. doi: 10.1111/acel.12506.
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