Tiospirone( —— )

Catalog No. M34041 CAS No. 87691-91-6

Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Tiospirone
Note

Research use only, not for human use.
Brief Description

Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.
Description

Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

Dopamine Receptor | 5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

87691-91-6
Formula Weight

440.6
Molecular Formula

C24H32N4O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C1N(C(=O)CC2(C1)CCCC2)CCCCN3CCN(C4=NSC=5C=CC=CC54)CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Arolfo MP, et, al. Effects of amperozide and tiospirone, atypical antipsychotic 5-HT2 drugs, on food-reinforced behavior in rats. Physiol Behav. 1999 Dec;68(1-2):93-8.?

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