Cart
sales@molnova.com
Home - Products - Angiogenesis - Bcl-2 - Thevetiaflavone

Thevetiaflavone

CAS No. 29376-68-9

Thevetiaflavone ( Apigenin-5-methyl ether; 2-Genistein-5-methyl ether )

Catalog No. M26581 CAS No. 29376-68-9

Thevetiaflavone could up-regulate the expression of Bcl 2 and down-regulate that of Bax and caspase 3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 785 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Thevetiaflavone
  • Note
    Research use only, not for human use.
  • Brief Description
    Thevetiaflavone could up-regulate the expression of Bcl 2 and down-regulate that of Bax and caspase 3.
  • Description
    Thevetiaflavone could up-regulate the expression of Bcl 2 and down-regulate that of Bax and caspase 3.(In Vitro):Thevetiaflavone reduces ROS overproduction and ameliorates ROS-mediated mitochondrial dysfunction, including collapse of mitochondrial membrane potential and opening of mitochondrial permeability transition pores, thereby reducing intracellular Ca2+ levels. Thevetiaflavone up-regulates the expression of Bcl-2, down-regulates the expression of Bax and caspase-3 and increases the activity of caspase-3 to inhibit the apoptosis of PC12 cells.
  • Synonyms
    Apigenin-5-methyl ether; 2-Genistein-5-methyl ether
  • Pathway
    Angiogenesis
  • Target
    Bcl-2
  • Recptor
    5-Lipoxygenase; prostaglandin synthetase (PGS)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    29376-68-9
  • Formula Weight
    284.3
  • Molecular Formula
    C16H12O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc(O)cc2oc(cc(=O)c12)-c1ccc(O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Katsumi I, et al. Studies on styrene derivatives. I. Synthesis and antiinflammatory activities of alpha-benzylidene-gamma-butyrolactone derivatives. Chem Pharm Bull (Tokyo). 1986 Jan;34(1):121-9.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • AZD 5991

    AZD 5991 (AZD5991) is a potent and selective macrocyclic inhibitor of Mcl-1 with sub-nanomolar affinity.

  • Dehydrocavidine

    Dehydrocavidine has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.

  • BCL6 inhibitor 14

    BCL6 inhibitor 14 is a potent BCL-6 inhibitor with FRET IC50 of 63 nM.

Sign In Join Free