Tenoxicam

CAS No. 59804-37-4

Tenoxicam( Ro 12-0068 )

Catalog No. M15222 CAS No. 59804-37-4

Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tenoxicam
  • Note
    Research use only, not for human use.
  • Brief Description
    Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
  • Description
    Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.(In Vitro):Tenoxicam (Ro-12-0068) is a non-steroidal anti-inflammatory drug (NSAID).(In Vivo):Tenoxicam (Ro-12-0068) was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam (Ro-12-0068) treatment. Tenoxicam (Ro-12-0068) also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia.
  • In Vitro
    Tenoxicam (Ro-12-0068) is a non-steroidal anti-inflammatory drug (NSAID).
  • In Vivo
    Tenoxicam (Ro-12-0068) was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam (Ro-12-0068) treatment. Tenoxicam (Ro-12-0068) also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia.
  • Synonyms
    Ro 12-0068
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    59804-37-4
  • Formula Weight
    337.37
  • Molecular Formula
    C13H11N3O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 68 mg/mL (201.55 mM)
  • SMILES
    O=C(C1=C(O)C2=C(C=CS2)S(N1C)(=O)=O)NC3=NC=CC=C3
  • Chemical Name
    4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yamada M, et al. J Pharmacol Exp Ther. 1997 May;281(2):1005-12.
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