Paeoniflorin

CAS No. 23180-57-6

Paeoniflorin( NSC 178886 )

Catalog No. M13654 CAS No. 23180-57-6

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 39 In Stock
50MG 53 In Stock
100MG 85 In Stock
200MG Get Quote In Stock
500MG 235 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Paeoniflorin
  • Note
    Research use only, not for human use.
  • Brief Description
    Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
  • Description
    Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.(In Vitro):Paeoniflorin (80 μg/mL; 4-24 h) treatment can induce Hsp40 and Hsp27 as well as Hsp70.(In Vivo):Paeoniflorin (intradermal injection; 25 and 100mg/kg; once daily; 20 days) shows favorable effects on experimental arthritis.
  • In Vitro
    Paeoniflorin (80 μg/mL; 4-24 h) treatment can induce Hsp40 and Hsp27 as well as Hsp70. Western Blot Analysis Cell Line:HeLa and IMR-32 cells Concentration:80 μg/mL Incubation Time:4, 8, 12, 16, and 24 hours Result:Promoted the phosphorylation of HSF1.
  • In Vivo
    Paeoniflorin (intradermal injection; 25 and 100mg/kg; once daily; 20 days) shows favorable effects on experimental arthritis. Animal Model:SD rats with collagen induced arthritis Dosage:25 and 100mg/kg Administration:Intradermal injection; 25 and 100mg/kg; once daily; 20 days Result:Decreased arthritis score, relieved ankle and paw swelling, improved spleen istopathology, decreased the levels of IgA, IgM, IgG and anti-CII antibody.
  • Synonyms
    NSC 178886
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    23180-57-6
  • Formula Weight
    480.46
  • Molecular Formula
    C23H28O11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 96mg/ml (199.81 mM); Water: 96mg/ml (199.81 mM); Ethanol: 96mg/ml (199.81 mM)
  • SMILES
    O[C@@H]([C@@H]([C@@H]([C@H](CO)O1)O)O)[C@H]1O[C@@]2(C3)C(C4)(C)OC5OC4(O)C3C25COC(C6=CC=CC=C6)=O
  • Chemical Name
    beta-D-Glucopyranoside, 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta(cd)pentalen-1a(2H)-yl, (1aR-(1a-alpha,2-beta,3a-alpha,5-alpha,5a-alpha,5b-alpha))

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cao BY, et al. J Ethnopharmacol, 2010. 131(1): p. 122-9.
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