Teniposide( NSC 122819; VM-26 )

Catalog No. M13908 CAS No. 29767-20-2

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Teniposide
Note

Research use only, not for human use.
Brief Description

Teniposide(VM-26) is a semisynthetic derivative of podophyllotoxin and are increasingly used in Y medicine.
Description

Teniposide(VM-26) is a semisynthetic derivative of podophyllotoxin and are increasingly used in Y medicine; causing breaks in DNA via an interaction with DNA topoisomerase II.
Synonyms

NSC 122819; VM-26
Pathway

Cell Cycle/DNA Damage
Target

Topoisomerase
Recptor

Topo II
Research Area

Cancer
Indication

——

CAS Number

29767-20-2
Formula Weight

656.66
Molecular Formula

C32H32O13S
Purity

>98%(HPLC)
Solubility

DMSO: 40 mg/mL (60.91 mM)
SMILES

O=C1OC[C@]2([H])[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@]4([H])O[C@H](C5=CC=CS5)OC[C@@]4([H])O3)C6=C(C=C7OCOC7=C6)[C@H](C8=CC(OC)=C(O)C(OC)=C8)[C@]21[H]
Chemical Name

(5S,5aR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)hexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one

1.de Lucio B, et al. Y Sci. 2005 Nov;96(11):774-83.

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