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Indotecan
CAS No. 915303-09-2
Indotecan ( LMP-400; NSC-724998 )
Catalog No. M24962 CAS No. 915303-09-2
Indotecan is an effective inhibitor of topoisomerase 1(Top1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 115 | In Stock |
|
| 10MG | 200 | In Stock |
|
| 25MG | 356 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIndotecan
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NoteResearch use only, not for human use.
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Brief DescriptionIndotecan is an effective inhibitor of topoisomerase 1(Top1).
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DescriptionIndotecan is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).
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SynonymsLMP-400; NSC-724998
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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Recptortopoisomerase I
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Research Area——
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Indication——
Chemical Information
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CAS Number915303-09-2
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Formula Weight478.5
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Molecular FormulaC26H26N2O7
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1N(CCCN2CCOCC2)C3=C(C(C4=C3C=C(OCO5)C5=C4)=O)C6=C1C=C(OC)C(OC)=C6
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Seol Y, et al. Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors. Mol Cancer Ther. 2015 Nov;14(11):2552-9.
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