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Talnetant
CAS No. 174636-32-9
Talnetant ( SB 223412 )
Catalog No. M20780 CAS No. 174636-32-9
Talnetant is a selective competitive brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | Get Quote |
|
| 5MG | 76 | Get Quote |
|
| 10MG | 119 | Get Quote |
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| 25MG | 251 | Get Quote |
|
| 50MG | 464 | Get Quote |
|
| 100MG | 705 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTalnetant
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NoteResearch use only not for human use.
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Brief DescriptionTalnetant is a selective competitive brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission.
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DescriptionTalnetant is a selective competitive brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission.
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SynonymsSB 223412
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorNK3
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Research AreaMetabolic Disease
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IndicationChronic obstructive pulmonary disease; Cough; Irritable bowel syndrome
Chemical Information
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CAS Number174636-32-9
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Formula Weight382.45
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Molecular FormulaC25H22N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (261.47 mM)
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SMILESCCC(NC(=O)c1c(O)c(-c2ccccc2)nc2ccccc12)c1ccccc1
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Chemical Name3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dawson L A Cato K J Scott C et al. In Vitro and In Vivo Characterization of the Non-peptide NK3 Receptor Antagonist SB-223412 (Talnetant): Potential Therapeutic Utility in the Treatment of Schizophrenia[J]. Neuropsychopharmacology 2008 33(7):1642-1652.
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