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Serlopitant

CAS No. 860642-69-9

Serlopitant( VPD-737 | MK-0594 )

Catalog No. M16236 CAS No. 860642-69-9

Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Serlopitant
  • Note
    Research use only, not for human use.
  • Brief Description
    Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.
  • Description
    Serlopitant (VPD-737, MK-0594) is a potent, selective substance P/neurokinin 1 (NK1) receptor for treating chronic pruritus.Alcoholism Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VPD-737 | MK-0594
  • Pathway
    GPCR/G Protein
  • Target
    Neurokinin Receptor
  • Recptor
    Neurokinin Receptor
  • Research Area
    Neurological Disease
  • Indication
    Alcoholism

Chemical Information

  • CAS Number
    860642-69-9
  • Formula Weight
    555.537
  • Molecular Formula
    C29H28F7NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1C=C(N2C[C@@]3([H])CC[C@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)[C@@H](C5=CC=C(F)C=C5)[C@]3([H])C2)CC1
  • Chemical Name
    3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yosipovitch G, et al. J Am Acad Dermatol. 2018 May;78(5):882-891.e10.
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