L-732138

CAS No. 148451-96-1

L-732138 ( —— )

Catalog No. M21568 CAS No. 148451-96-1

L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 40 Get Quote
5MG 65 Get Quote
10MG 110 Get Quote
25MG 205 Get Quote
50MG 357 Get Quote
100MG 530 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    L-732138
  • Note
    Research use only not for human use.
  • Brief Description
    L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM).
  • Description
    L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM).
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Neurokinin Receptor
  • Recptor
    NK-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    148451-96-1
  • Formula Weight
    472.38
  • Molecular Formula
    C22H18F6N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F
  • Chemical Name
    [35-Bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mu?oz M et al. The NK-1 Receptor Antagonist L-732138 Induces Apoptosis and Counteracts Substance P-Related Mitogenesis in Human Melanoma Cell Lines. Cancers (Basel). 2010 Apr 20;2(2):611-23.
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