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TNKS-2-IN-1
CAS No. 4765-59-7
TNKS-2-IN-1( —— )
Catalog No. M37041 CAS No. 4765-59-7
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 28 | In Stock |
|
| 25MG | 40 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTNKS-2-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionTNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.
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DescriptionTNKS-2-IN-1 (Compound 13g) is a TNKS-2 inhibitor. TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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RecptorWnt/beta-catenin | PARP | Antibiotic
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Research Area——
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Indication——
Chemical Information
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CAS Number4765-59-7
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Formula Weight267.24
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Molecular FormulaC14H9N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 1 mg/mL (3.74 mM; Ultrasonic (<60°C)
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SMILES[O-][N+](=O)c1ccc(cc1)-c1nc(=O)c2ccccc2[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nathubhai A, et al. Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases. Eur J Med Chem. 2016 Aug 8;118:316-27.?
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