β-catenin modulator IIa-661
CAS No. 1015859-04-7
β-catenin modulator IIa-661( —— )
Catalog No. M36051 CAS No. 1015859-04-7
β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
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| 5MG | 48 | In Stock |
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| 10MG | 72 | In Stock |
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| 25MG | 124 | In Stock |
|
| 50MG | 186 | In Stock |
|
| 100MG | 272 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Nameβ-catenin modulator IIa-661
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NoteResearch use only, not for human use.
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Brief Descriptionβ-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.
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Descriptionβ-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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RecptorWnt/beta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number1015859-04-7
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Formula Weight394.92
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Molecular FormulaC19H23ClN2O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESC(S(CC(NC1CCCCC1)=O)=O)C=2N=C(OC2C)C3=CC=C(Cl)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Carboxylesterase-IN-...
Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.
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Wnt pathway activato...
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM. Wnt pathway activator 1 is a potent Wnt activator for the treatment of androgenetic alopecia (AGA) extracted from patent WO2012024404A1.
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NRX-252114 B
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.
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