
BNC-1
CAS No. 96335-59-0
BNC-1( BNC-1 | BNC 1 | BNC1 )
Catalog No. M16864 CAS No. 96335-59-0
BNC-1 is a small molecule modulator of Amyloid pathology by promoting phosphorylation and activation of Elk-1.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 873 | Get Quote |
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50MG | 1782 | Get Quote |
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100MG | 2250 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameBNC-1
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NoteResearch use only, not for human use.
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Brief DescriptionBNC-1 is a small molecule modulator of Amyloid pathology by promoting phosphorylation and activation of Elk-1.
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DescriptionBNC-1 is a small molecule modulator of Amyloid pathology by promoting phosphorylation and activation of Elk-1, a transcriptional repressor of presenilin-1 but not presenilin-2; increases levels of synaptophysin and synapsin, markers of synaptic integrity, but does not adversely impact presenilin-2 or processing of Notch-1, significantly decreases amyloid burden and improves markers of synaptic integrity in a well-established mouse model of amyloid deposition.
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In Vitro——
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In Vivo——
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SynonymsBNC-1 | BNC 1 | BNC1
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PathwayOthers
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TargetAmyloids
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RecptorAmyloids
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Research Area——
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Indication——
Chemical Information
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CAS Number96335-59-0
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Formula Weight282.299
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Molecular FormulaC16H14N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C(C(C)=NC(C)=C12)=C2C3=CC=CC=C3NC1=O)OC
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Chemical NameMethyl 2,4-dimethyl-5-oxo-5,6-dihydrobenzo[c][2,7]naphthyridine-1-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lovell MA, et al. J Alzheimers Dis. 2016 May 4;53(1):273-87.
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