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Sutezolid
CAS No. 168828-58-8
Sutezolid( PNU-100480 | PNU100480 | PF-02341272 | PF02341272 | U-100480 )
Catalog No. M12576 CAS No. 168828-58-8
An oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 50 | In Stock |
|
| 10MG | 87 | In Stock |
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| 25MG | 177 | In Stock |
|
| 50MG | 290 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | 654 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSutezolid
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NoteResearch use only, not for human use.
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Brief DescriptionAn oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo.
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DescriptionAn oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo; significantly shorten the duration of therapy for drug-susceptible as well as multidrug-resistant tuberculosis.Bacterial Infection Phase 2 Clinical(In Vitro):Sutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of Mycobacterium avium complex (MIC’s=0.5-4 μg/mL).(In Vivo):Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models.
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In VitroSutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of Mycobacterium avium complex (MIC’s=0.5-4 μg/mL).
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In VivoSutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models.
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SynonymsPNU-100480 | PNU100480 | PF-02341272 | PF02341272 | U-100480
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaInfection
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IndicationBacterial Infection
Chemical Information
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CAS Number168828-58-8
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Formula Weight353.4117
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Molecular FormulaC16H20FN3O3S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(NC[C@H]1CN(C2=CC=C(N3CCSCC3)C(F)=C2)C(O1)=O)=O
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Chemical NameAcetamide, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cynamon MH, et al. Antimicrob Agents Chemother. 1999 May;43(5):1189-91.
2. Williams KN, et al. Antimicrob Agents Chemother. 2009 Apr;53(4):1314-9.
3. Williams KN, et al. Am J Respir Crit Care Med. 2009 Aug 15;180(4):371-6.
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