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IDI-6273

CAS No. 433945-73-4

IDI-6273( IDI6273 )

Catalog No. M14478 CAS No. 433945-73-4

A potent, mutant-selective PfDHODH inhibitor with IC50 of 210 nM for 3D7 E182D PfDHODH.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

IDI-6273
Note

Research use only, not for human use.
Brief Description

A potent, mutant-selective PfDHODH inhibitor with IC50 of 210 nM for 3D7 E182D PfDHODH.
Description

A potent, mutant-selective PfDHODH inhibitor with IC50 of 210 nM for 3D7 E182D PfDHODH; displays 10.95-fold more active against 3D7 E182D than 3D7; does not yield resistant parasites with a combination of Genz-669178.
In Vitro

——
In Vivo

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Synonyms

IDI6273
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

433945-73-4
Formula Weight

341.835
Molecular Formula

C20H20ClNO2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

2-(4-chlorobenzyl)-8-ethoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lukens AK, e tal. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):799-804.

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