SMARt-420 ( BDM 41420 )

Catalog No. M12355 CAS No. 1616242-21-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

SMARt-420
Note

Research use only, not for human use.
Brief Description

SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice.
Description

SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice, also increases the basal sensitivity of bacteria to ethionamide.
Synonyms

BDM 41420
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

CAS Number

1616242-21-7
Formula Weight

340.35
Molecular Formula

C17H19F3N2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

4,4,4-Trifluoro-1-(3-phenyl-1-oxa-2,8-diaza-spiro[4.5]dec-2-en-8-yl)-butan-1-one

1. Blondiaux N, et al. Science. 2017 Mar 17;355(6330):1206-1211.
2. Wohlknig A, et al. Biochem Biophys Res Commun. 2017 May 27;487(2):403-408.

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