Suprastat( )

Catalog No. M28984 CAS No. 90093-40-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Suprastat
Note

Research use only, not for human use.
Brief Description

Suprastat is an HDAC6 inhibitor used in silico simulations.
Description

Suprastat is an HDAC6 inhibitor used in silico simulations.(In Vitro):Suprastat demonstrates subnanomolar HDAC6 inhibitory potency and a hundred- to a thousand-fold HDAC6 selectivity over the other HDAC isoforms.(In Vivo):In vivo studies reveal that a combination of Suprastat and anti-PD1 immunotherapy enhances antitumor immune response, mediated by a decrease of protumoral M2 macrophages and increased infiltration of antitumor CD8+ effector and memory T-cells.
In Vitro
In Vivo
Synonyms
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor
Research Area
Indication

1.Blunt J W , Copp B R , Keyzers R A , et al. Marine natural products[J]. Natural Product Reports, 2016, 33.

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