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Home - Products - Cell Cycle/DNA Damage - HDAC - CGK-1026

CGK-1026

CAS No. 287383-59-9

CGK-1026 ( CGK 1026;CGK1026 )

Catalog No. M13877 CAS No. 287383-59-9

A small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 88 In Stock
25MG 194 In Stock
50MG 357 In Stock
100MG 537 In Stock
500MG 1134 In Stock
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Biological Information

  • Product Name
    CGK-1026
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression.
  • Description
    A small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression; inhibits the recruitment of HDAC into E2F-pocket protein complexes assembled on the hTERT promoter, inhibits HDAC activity with IC50 of 100 nM; induces G1 arrest of IMR90 cells.
  • Synonyms
    CGK 1026;CGK1026
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    287383-59-9
  • Formula Weight
    326.35
  • Molecular Formula
    C18H18N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 32.6 mg/mL (100 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    O=C(NO)CCCCCN(C(C1=CC=CC2=CC=CC3=C12)=O)C3=O
  • Chemical Name
    N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Won J, et al. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11328-33.
2. Alimirah F, et al. Mol Cancer Res. 2007 Mar;5(3):251-9.
3. Song LL, et al. PLoS One. 2010 Jan 5;5(1):e8569.
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