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CPA-7
CAS No. 16961-77-6
CPA-7( CPA 7 | CPA7 )
Catalog No. M12586 CAS No. 16961-77-6
A platinum-containing compound that disrupts STAT3 signaling, inhibits cell growth and induces apoptosis in STAT3-activated cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCPA-7
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NoteResearch use only, not for human use.
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Brief DescriptionA platinum-containing compound that disrupts STAT3 signaling, inhibits cell growth and induces apoptosis in STAT3-activated cancer cells.
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DescriptionA platinum-containing compound that disrupts STAT3 signaling, inhibits cell growth and induces apoptosis in STAT3-activated cancer cells; selectively and significantly inhibits Stat3 activation and DNA-binding activity, induces regression of colon tumors in mouse model at 5mg/kg, with the abrogation of persistent Stat3 activity in tumors.
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In Vitro——
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In Vivo——
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SynonymsCPA 7 | CPA7
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number16961-77-6
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Formula Weight381.501
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Molecular FormulaCl3H6N3O2Pt
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NamePlatinum, diamminetrichloronitro- (8CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Turkson J, et al. Mol Cancer Ther. 2004 Dec;3(12):1533-42.
2. Assi HH, et al. J Pharmacol Exp Ther. 2014 Jun;349(3):458-69.
3. Littlefield SL, et al. Inorg Chem. 2008 Apr 7;47(7):2798-804.
4. Liang M, et al. BMC Cancer. 2016 Jul 19;16:504.
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