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STA-21
CAS No. 28882-53-3
STA-21( NSC 628869 | Ochromycinone )
Catalog No. M13885 CAS No. 28882-53-3
A small-molecule inhibitor of STAT3; inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSTA-21
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NoteResearch use only, not for human use.
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Brief DescriptionA small-molecule inhibitor of STAT3; inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM).
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DescriptionA small-molecule inhibitor of STAT3; inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM); reduces the survival of breast carcinoma cells with constitutive Stat3 signaling; inhibits cell viability and growth and induces apoptosis through caspases 3, 8 and 9 pathways in human sarcoma cell lines.
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In Vitro——
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In Vivo——
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SynonymsNSC 628869 | Ochromycinone
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number28882-53-3
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Formula Weight306.3
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Molecular FormulaC19H14O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O
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Chemical Name(3S)-3,4-dihydro-8-hydroxy-3-methyl-benz[a]anthracene-1,7,12(2H)-trione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Song H, et al. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4700-5.
2. Chen CL, et al. BMC Cancer. 2007 Jun 28;7:111.
3. Fuh B, et al. Br J Cancer. 2009 Jan 13;100(1):106-12.
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