Cart
sales@molnova.com
STA-21
CAS No. 28882-53-3
STA-21( NSC 628869 | Ochromycinone )
Catalog No. M13885 CAS No. 28882-53-3
A small-molecule inhibitor of STAT3; inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSTA-21
-
NoteResearch use only, not for human use.
-
Brief DescriptionA small-molecule inhibitor of STAT3; inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM).
-
DescriptionA small-molecule inhibitor of STAT3; inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity (20-30 uM); reduces the survival of breast carcinoma cells with constitutive Stat3 signaling; inhibits cell viability and growth and induces apoptosis through caspases 3, 8 and 9 pathways in human sarcoma cell lines.
-
In Vitro——
-
In Vivo——
-
SynonymsNSC 628869 | Ochromycinone
-
PathwayJAK/STAT Signaling
-
TargetSTAT
-
RecptorSTAT
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number28882-53-3
-
Formula Weight306.3
-
Molecular FormulaC19H14O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O
-
Chemical Name(3S)-3,4-dihydro-8-hydroxy-3-methyl-benz[a]anthracene-1,7,12(2H)-trione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Song H, et al. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4700-5.
2. Chen CL, et al. BMC Cancer. 2007 Jun 28;7:111.
3. Fuh B, et al. Br J Cancer. 2009 Jan 13;100(1):106-12.
molnova catalog
related products
-
AC-4-130
AC-4-130 is a novel, potent STAT5 SH2 domain inhibitor, binds to and efficiently blocks STAT5 activation and subsequent transcriptional activity.
-
Palivizumab
Palivizumab (MEDI 493) is a humanized RSV-specific monoclonal antibody that selectively inhibits epitopes at the F protein A antigenic site of RSV subtypes A and B for the prevention of respiratory syncytial virus infection (RSV).
-
STAT3-IN-1
STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumor apoptosis.
