Cart
sales@molnova.com
Home - Products - JAK/STAT Signaling - STAT - Stafib-1

Stafib-1

CAS No. 1688703-26-5

Stafib-1( Stafib 1 )

Catalog No. M12577 CAS No. 1688703-26-5

A potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 44 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Stafib-1
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 44 nM.
  • Description
    A potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 44 nM, >50-fold selectivity over STAT5a.
  • In Vitro
    Stafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a.
  • In Vivo
    ——
  • Synonyms
    Stafib 1
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1688703-26-5
  • Formula Weight
    602.429
  • Molecular Formula
    C26H24N2O11P2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (166.00 mM)
  • SMILES
    O=C(NCC1=CC=C(OP(O)(O)=O)C(OP(O)(O)=O)=C1)COC2=CC=C3C=C(C(NC4=CC=CC=C4)=O)C=CC3=C2
  • Chemical Name
    4-((2-((6-(phenylcarbamoyl)naphthalen-2-yl)oxy)acetamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Elumalai N, et al. Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4758-63. 2. Elumalai N, et al. Sci Rep. 2017 Apr 11;7(1):819.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Fludarabine

    Fludarabine(NSC 118218), a DNA synthesis inhibitor.

  • Nirsevimab

    Nirsevimab (MEDI8897) is a recombinant human respiratory syncytial virus (RSV) monoclonal antibody with a modified Fc region, efficiently targeting RSV-B with a Kd value of 1.5 nM, and can be used to prevent RSV infection.

  • LLL-12

    A nonpeptide, cell-permeable STAT3 inhibitor that binds directly to the pTyr705 binding site of the STAT3 monomer.

Sign In Join Free