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STAT5-IN-1
CAS No. 285986-31-4
STAT5-IN-1 ( Signal Transducers and Activators of Transcription 5 )
Catalog No. M13870 CAS No. 285986-31-4
A selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 42 | In Stock |
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| 10MG | 77 | In Stock |
|
| 25MG | 165 | In Stock |
|
| 50MG | 290 | In Stock |
|
| 100MG | 492 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSTAT5-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionA selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays.
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DescriptionA selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays; shows little to no inhibition for STAT1, STAT3 and Lck (<40% inhibition at 500 uM); selectively inhibits the function of the STAT5b domain and STAT5 DNA binding in vitro, and selectively inhibits activation of STAT5 in K562 cells.
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SynonymsSignal Transducers and Activators of Transcription 5
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT5β
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number285986-31-4
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Formula Weight293.28
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Molecular FormulaC16H11N3O3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥23.0 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(N/N=C/C1=COC2=C(C=CC=C2)C1=O)C3=CN=CC=C3
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Chemical Name3-Pyridinecarboxylic acid, [(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Müller J, et al. Chembiochem. 2008 Mar 25; 9(5):723-7.
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