RSV-IN-1
CAS No. 861139-16-4
RSV-IN-1 ( —— )
Catalog No. M26424 CAS No. 861139-16-4
RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 200 | Get Quote |
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10MG | 341 | Get Quote |
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25MG | 563 | Get Quote |
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50MG | 795 | Get Quote |
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100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameRSV-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionRSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
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DescriptionRSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.(In Vitro):The concentration of RSV-IN-1 that reduced the viability of HEp-2 cells by 50% was 310μM. RSV-IN-1 exhibited no direct virucidal activity or inhibitory effects on the virus attachment to cells. However, to inhibit formation of RSV-induced syncytial plaques RSV-IN-1 had to be present during the virus entry into the cells and the cell-to-cell transmission of the virus. The RSV multiplication in HEp-2 cells in the presence of RSV-IN-1 resulted in rapid selection of viral variants that were ~1000 times less sensitive to these drugs than original virus.
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Synonyms——
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorAndrogen Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number861139-16-4
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Formula Weight427.5
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Molecular FormulaC20H21N5O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESCOc1ccc(cc1-c1nnc2c3ccccc3c(C)nn12)S(=O)(=O)N(C)CCO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Schlienger N, et al. Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators. J Med Chem. 2009 Nov 26;52(22):7186-91.
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