RSV-IN-1

CAS No. 861139-16-4

RSV-IN-1 ( —— )

Catalog No. M26424 CAS No. 861139-16-4

RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 200 Get Quote
10MG 341 Get Quote
25MG 563 Get Quote
50MG 795 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    RSV-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
  • Description
    RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.(In Vitro):The concentration of RSV-IN-1 that reduced the viability of HEp-2 cells by 50% was 310μM. RSV-IN-1 exhibited no direct virucidal activity or inhibitory effects on the virus attachment to cells. However, to inhibit formation of RSV-induced syncytial plaques RSV-IN-1 had to be present during the virus entry into the cells and the cell-to-cell transmission of the virus. The RSV multiplication in HEp-2 cells in the presence of RSV-IN-1 resulted in rapid selection of viral variants that were ~1000 times less sensitive to these drugs than original virus.
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    Androgen Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    861139-16-4
  • Formula Weight
    427.5
  • Molecular Formula
    C20H21N5O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccc(cc1-c1nnc2c3ccccc3c(C)nn12)S(=O)(=O)N(C)CCO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schlienger N, et al. Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators. J Med Chem. 2009 Nov 26;52(22):7186-91.
molnova catalog
related products
  • Hydrazinocurcumin

    Hydrazinocurcumin is a synthetic curcumin derivative that inhibits the proliferation of bovine aortic endothelial cells (BAECs) with IC50 of 520 nM without cytotoxicity.

  • IQDMA

    A cell-permeable, small molecule inhibitor of the transcription factor STAT5.

  • HO-3867

    A synthetic curcuminoid that selectively inhibits STAT3 phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs.