Stafia-1( —— )

Catalog No. M28612 CAS No. 2582757-90-0

Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Stafia-1
Note

Research use only, not for human use.
Brief Description

Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
Description

Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
In Vitro

Stafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other STAT family members.
In Vivo

——
Synonyms

——
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

NOP receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

2582757-90-0
Formula Weight

506.44
Molecular Formula

C24H27O10P
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (493.64 mM)
SMILES

COC1=CC(C2=CC(OP(O)(O)=O)=CC(C3=CC(OC)=C(OC)C(OC)=C3)=C2)=CC(OC)=C1OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Thomsen C, Hohlweg R. (8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4. 5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist. Br J Pharmacol. 2000 Nov;131(5):903-8.

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