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Stafia-1

CAS No. 2582757-90-0

Stafia-1( —— )

Catalog No. M28612 CAS No. 2582757-90-0

Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Stafia-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
  • Description
    Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
  • In Vitro
    Stafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other STAT family members.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    NOP receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2582757-90-0
  • Formula Weight
    506.44
  • Molecular Formula
    C24H27O10P
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (493.64 mM)
  • SMILES
    COC1=CC(C2=CC(OP(O)(O)=O)=CC(C3=CC(OC)=C(OC)C(OC)=C3)=C2)=CC(OC)=C1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Thomsen C, Hohlweg R. (8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4. 5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist. Br J Pharmacol. 2000 Nov;131(5):903-8.
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