Cart
sales@molnova.com
ML116
CAS No. 744270-00-6
ML116 ( ML 116;ML-116 )
Catalog No. M15840 CAS No. 744270-00-6
A novel selective STAT3 inhibitor with IC50 of 4.2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 178 | Get Quote |
|
| 5MG | 267 | Get Quote |
|
| 10MG | 408 | Get Quote |
|
| 25MG | 672 | Get Quote |
|
| 50MG | 945 | Get Quote |
|
| 100MG | 1278 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameML116
-
NoteResearch use only, not for human use.
-
Brief DescriptionA novel selective STAT3 inhibitor with IC50 of 4.2 uM.
-
DescriptionA novel selective STAT3 inhibitor with IC50 of 4.2 uM, does not inhibit STAT1, STAT5, or NFkB signaling pathways (IC50>50 uM); inhibits transcription of the STAT3-regulated gene BCL3, sslectively induces loss of viability of breast cancer cell lines such as MDA-MB-468 cells.
-
SynonymsML 116;ML-116
-
PathwayJAK/STAT Signaling
-
TargetSTAT
-
RecptorSTAT
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number744270-00-6
-
Formula Weight309.43
-
Molecular FormulaC18H19N3S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1CN(CCC1CC2=CC=CC=C2)C3=C4C=CSC4=NC=N3
-
Chemical Name4-benzyl-1-{thieno[2,3-d]pyrimidin-4-yl}piperidine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Assi HH, et al. J Pharmacol Exp Ther. 2014 Jun;349(3):458-69.
2. Madoux F, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Madoux F, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
molnova catalog
related products
