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ML116

CAS No. 744270-00-6

ML116( ML 116 | ML-116 )

Catalog No. M15840 CAS No. 744270-00-6

A novel selective STAT3 inhibitor with IC50 of 4.2 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 178 Get Quote
5MG 267 Get Quote
10MG 408 Get Quote
25MG 672 Get Quote
50MG 945 Get Quote
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Biological Information

  • Product Name
    ML116
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel selective STAT3 inhibitor with IC50 of 4.2 uM.
  • Description
    A novel selective STAT3 inhibitor with IC50 of 4.2 uM, does not inhibit STAT1, STAT5, or NFkB signaling pathways (IC50>50 uM); inhibits transcription of the STAT3-regulated gene BCL3, sslectively induces loss of viability of breast cancer cell lines such as MDA-MB-468 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ML 116 | ML-116
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    744270-00-6
  • Formula Weight
    309.431
  • Molecular Formula
    C18H19N3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1CN(CCC1CC2=CC=CC=C2)C3=C4C=CSC4=NC=N3
  • Chemical Name
    4-benzyl-1-{thieno[2,3-d]pyrimidin-4-yl}piperidine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Assi HH, et al. J Pharmacol Exp Ther. 2014 Jun;349(3):458-69. 2. Madoux F, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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