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CAY10784
CAS No. 1245814-52-1
CAY10784( —— )
Catalog No. M34813 CAS No. 1245814-52-1
CAY10784 (STAT3-IN-17) is a STAT3 inhibitor with antiproliferative and antitumor activities. CAY10784 showed antibacterial activity against Clostridium difficile.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 90 | Get Quote |
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| 5MG | 202 | Get Quote |
|
| 10MG | 353 | Get Quote |
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| 25MG | 724 | Get Quote |
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| 50MG | 1159 | Get Quote |
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| 100MG | 1782 | Get Quote |
|
| 200MG | 2457 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCAY10784
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NoteResearch use only, not for human use.
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Brief DescriptionCAY10784 (STAT3-IN-17) is a STAT3 inhibitor with antiproliferative and antitumor activities. CAY10784 showed antibacterial activity against Clostridium difficile.
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DescriptionSTAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT | Antibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number1245814-52-1
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Formula Weight317.24
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Molecular FormulaC11H6F3N3O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC=C(C(F)(F)F)C=C1)NC2=NC=C([N+]([O-])=O)S2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lü Z, et al. Structure-Activity Study of Nitazoxanide Derivatives as Novel STAT3 Pathway Inhibitors. ACS Med Chem Lett. 2021 Apr 1;12(5):696-703. ?
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