Spastazoline

CAS No. 2351882-11-4

Spastazoline ( —— )

Catalog No. M21959 CAS No. 2351882-11-4

Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 102 In Stock
10MG 170 In Stock
25MG 340 In Stock
50MG 511 In Stock
100MG 734 In Stock
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Biological Information

  • Product Name
    Spastazoline
  • Note
    Research use only, not for human use.
  • Brief Description
    Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).?
  • Description
    Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM).?
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    spastin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2351882-11-4
  • Formula Weight
    382.51
  • Molecular Formula
    C20H30N8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:95 mg/ml(248.36 mM; Need ultrasonic)
  • SMILES
    CC(C)[C@@H]1CN(CCN1)c1nc(Nc2cc([nH]n2)C(C)(C)C)c2cc[nH]c2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cupido T, et al. Designing a chemical inhibitor for the AAA protein spastin using active site mutations. Nat Chem Biol. 2019 Feb 18.2. Pisa R , Cupido T , Steinman J B , et al. Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins[J]. Cell Chemical Biology, 2019, 26(9).
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