Spastazoline( —— )

Catalog No. M21959 CAS No. 2351882-11-4

Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).?

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Spastazoline
Note

Research use only, not for human use.
Brief Description

Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).?
Description

Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM).?
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

spastin
Research Area

——
Indication

——

Chemical Information

CAS Number

2351882-11-4
Formula Weight

382.51
Molecular Formula

C20H30N8
Purity

>98% (HPLC)
Solubility

DMSO:95 mg/ml(248.36 mM; Need ultrasonic)
SMILES

CC(C)[C@@H]1CN(CCN1)c1nc(Nc2cc([nH]n2)C(C)(C)C)c2cc[nH]c2n1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Cupido T, et al. Designing a chemical inhibitor for the AAA protein spastin using active site mutations. Nat Chem Biol. 2019 Feb 18.2. Pisa R , Cupido T , Steinman J B , et al. Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins[J]. Cell Chemical Biology, 2019, 26(9).

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