SW155246 ( —— )

Catalog No. M24384 CAS No. 420092-79-1

SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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5MG	65	In Stock
10MG	105	In Stock
25MG	213	In Stock
50MG	340	In Stock
100MG	537	In Stock
500MG	1152	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SW155246
Note

Research use only, not for human use.
Brief Description

SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).
Description

SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

DNMT1
Research Area

——
Indication

——

Chemical Information

CAS Number

420092-79-1
Formula Weight

378.8
Molecular Formula

C16H11ClN2O5S
Purity

>98% (HPLC)
Solubility

——
SMILES

C1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Medina-Franco J , O Méndez-Lucio, Yoo J . Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking[J]. International Journal of Molecular Sciences, 2014, 15(2).

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