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Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - SW155246

SW155246

CAS No. 420092-79-1

SW155246 ( —— )

Catalog No. M24384 CAS No. 420092-79-1

SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 105 In Stock
25MG 213 In Stock
50MG 340 In Stock
100MG 537 In Stock
500MG 1152 In Stock
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Biological Information

  • Product Name
    SW155246
  • Note
    Research use only, not for human use.
  • Brief Description
    SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).
  • Description
    SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNMT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    420092-79-1
  • Formula Weight
    378.8
  • Molecular Formula
    C16H11ClN2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Medina-Franco J , O Méndez-Lucio, Yoo J . Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking[J]. International Journal of Molecular Sciences, 2014, 15(2).
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