Asiaticoside( Asiaticoside | Ba 2742 | BRN0078195 | CCRIS8995 | NSC166062 )

Catalog No. M17362 CAS No. 16830-15-2

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Asiaticoside
Note

Research use only, not for human use.
Brief Description

Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns.
Description

Asiaticoside is a skin whiening agent found in Cetella. It decreases DNA binding by MITF. It also induces apoptosis in breast cancer cells, improves memory and learning deficits, decreases release of pro-inflammatory cytokines, and suppresses LPS-induced inflammation and fever.
In Vitro

——
In Vivo

——
Synonyms

Asiaticoside | Ba 2742 | BRN0078195 | CCRIS8995 | NSC166062
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

p38 MAPK| TGFβ1
Research Area

Others-Field
Indication

——

CAS Number

16830-15-2
Formula Weight

959.15
Molecular Formula

C48H78O19
Purity

>98% (HPLC)
Solubility

DMSO : 50 mg/mL. 52.13 mM;
SMILES

[C@]12([C@H]([C@@]([C@@H]([C@@H](C1)O)O)(CO)C)CC[C@@]1([C@@H]2CC=C2[C@]1(CC[C@@]1([C@H]2[C@H]([C@@H](CC1)C)C)C(=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)O)O)O)O)O)C)C)C
Chemical Name

(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl (1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate

1. Luo Y, et al. Mol Med Rep. 2015 Dec;12(6):8294-300.

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