SW-106065

CAS No. 62289-81-0

SW-106065 ( SW106065;MPNST-IN-21 )

Catalog No. M15357 CAS No. 62289-81-0

SW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 57 Get Quote
5MG 98 Get Quote
10MG 155 Get Quote
25MG 282 Get Quote
50MG 444 Get Quote
100MG 653 Get Quote
500MG 1368 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SW-106065
  • Note
    Research use only, not for human use.
  • Brief Description
    SW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).
  • Description
    SW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors); inhibits ATP consumption of sMPNST and other models of MPNST with EC50 of 1 uM, shows no toxicity to normally dividing Schwann cells or mouse embryonic fibroblasts; reduces MPNST burden in a mouse allograft model.
  • Synonyms
    SW106065;MPNST-IN-21
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    62289-81-0
  • Formula Weight
    204.25
  • Molecular Formula
    C10H8N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC(=CN=C1)NC(=O)C2=CC=CS2
  • Chemical Name
    N-(pyridin-3-yl)thiophene-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chau V, et al. Cancer Res. 2014 Jan 15;74(2):586-97.
molnova catalog
related products
  • UCF 101

    UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.

  • Millepachine

    Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.

  • Eriocalyxin B

    Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment.