SW-106065
CAS No. 62289-81-0
SW-106065 ( SW106065;MPNST-IN-21 )
Catalog No. M15357 CAS No. 62289-81-0
SW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 57 | Get Quote |
|
5MG | 98 | Get Quote |
|
10MG | 155 | Get Quote |
|
25MG | 282 | Get Quote |
|
50MG | 444 | Get Quote |
|
100MG | 653 | Get Quote |
|
500MG | 1368 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSW-106065
-
NoteResearch use only, not for human use.
-
Brief DescriptionSW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).
-
DescriptionSW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors); inhibits ATP consumption of sMPNST and other models of MPNST with EC50 of 1 uM, shows no toxicity to normally dividing Schwann cells or mouse embryonic fibroblasts; reduces MPNST burden in a mouse allograft model.
-
SynonymsSW106065;MPNST-IN-21
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number62289-81-0
-
Formula Weight204.25
-
Molecular FormulaC10H8N2OS
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1=CC(=CN=C1)NC(=O)C2=CC=CS2
-
Chemical NameN-(pyridin-3-yl)thiophene-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chau V, et al. Cancer Res. 2014 Jan 15;74(2):586-97.
molnova catalog
related products
-
Myristoleic acid
Myristoleic acid is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.
-
SF5
SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.
-
Sophoraflavanone G
Sophoraflavanone G (Kushenol F) isolated from Sophora flavescens induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways.