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QD 232

CAS No. 1527467-32-8

QD 232( QD232 )

Catalog No. M12137 CAS No. 1527467-32-8

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

QD 232
Note

Research use only, not for human use.
Brief Description

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation.
Description

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation, decreasing pancreatic cancer cell viability and migration; arrests cell cycle progression and induces apoptosis at low micromolar concentrations, shows effectivity in drug-resistant cancer cell lines.
In Vitro

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In Vivo

——
Synonyms

QD232
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

STAT
Research Area

——
Indication

——

Chemical Information

CAS Number

1527467-32-8
Formula Weight

293.282
Molecular Formula

C16H11N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

6-((3-acetylphenyl)amino)quinazoline-5,8-dione

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pathania D, et al. Br J Pharmacol. 2015 Jan;172(1):50-63. 2. Kuang Y, et al. J Med Chem. 2018 Feb 22;61(4):1576-1594.

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