ST-034307

CAS No. 133406-29-8

ST-034307 ( ST 034307;ST034307 )

Catalog No. M11327 CAS No. 133406-29-8

ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 Get Quote
5MG 67 Get Quote
10MG 105 Get Quote
25MG 223 Get Quote
50MG 383 Get Quote
100MG 569 Get Quote
500MG 1215 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ST-034307
  • Note
    Research use only, not for human use.
  • Brief Description
    ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM.
  • Description
    ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM; shows no activity against other AC isoforms; inhibits Ca2+-stimulated cAMP accumulation in HEK cells, also inhibits AC1 activity stimulated by forskolin- and Gαs-coupled receptors in HEK-AC1 cells; reduces pain responses in a mouse model of inflammatory pain.
  • Synonyms
    ST 034307;ST034307
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Adenylate Cyclase
  • Recptor
    Adenylate Cyclase
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    133406-29-8
  • Formula Weight
    297.95
  • Molecular Formula
    C10H4Cl4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL 167.81 mM
  • SMILES
    O=C1C=C(C(Cl)(Cl)Cl)OC2=C1C=C(Cl)C=C2
  • Chemical Name
    6-chloro-2-(trichloromethyl)-4H-chromen-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brust TF, et al. Sci Signal. 2017 Feb 21;10(467). pii: eaah5381.
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