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Home - Products - Metabolic Enzyme/Protease - Adenylate Cyclase - ST-034307

ST-034307

CAS No. 133406-29-8

ST-034307 ( ST 034307;ST034307 )

Catalog No. M11327 CAS No. 133406-29-8

ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ST-034307
  • Note
    Research use only, not for human use.
  • Brief Description
    ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM.
  • Description
    ST-034307 (ST 034307, ST034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM; shows no activity against other AC isoforms; inhibits Ca2+-stimulated cAMP accumulation in HEK cells, also inhibits AC1 activity stimulated by forskolin- and Gαs-coupled receptors in HEK-AC1 cells; reduces pain responses in a mouse model of inflammatory pain.
  • Synonyms
    ST 034307;ST034307
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Adenylate Cyclase
  • Recptor
    Adenylate Cyclase
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    133406-29-8
  • Formula Weight
    297.95
  • Molecular Formula
    C10H4Cl4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL 167.81 mM
  • SMILES
    O=C1C=C(C(Cl)(Cl)Cl)OC2=C1C=C(Cl)C=C2
  • Chemical Name
    6-chloro-2-(trichloromethyl)-4H-chromen-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brust TF, et al. Sci Signal. 2017 Feb 21;10(467). pii: eaah5381.
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