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Home - Products - Metabolic Enzyme/Protease - Adenylate Cyclase - NKY80

NKY80

CAS No. 299442-43-6

NKY80 ( NKY 80;NKY-80 )

Catalog No. M13924 CAS No. 299442-43-6

A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 35 Get Quote
5MG 56 Get Quote
10MG 87 Get Quote
25MG 177 Get Quote
50MG 309 Get Quote
100MG 471 Get Quote
200MG 678 Get Quote
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Biological Information

  • Product Name
    NKY80
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.
  • Description
    A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively; displays little to no activity for other AC isoforms (IC50>100 uM); blocks both BAPTA-AM-stimulated cAMP formation and renin release in primary cultures of juxtaglomerular cells.
  • Synonyms
    NKY 80;NKY-80
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Adenylate Cyclase
  • Recptor
    Adenylate Cyclase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    299442-43-6
  • Formula Weight
    229.24
  • Molecular Formula
    C12H11N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1C2=CN=C(N)N=C2CC(C3=CC=CO3)C1
  • Chemical Name
    2-amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Onda T, et al. J Biol Chem. 2001 Dec 21;276(51):47785-93.
2. Ortiz-Capisano MC, et al. Hypertension. 2007 Mar;49(3):618-24.
3. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
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