NKY80

CAS No. 299442-43-6

NKY80 ( NKY 80;NKY-80 )

Catalog No. M13924 CAS No. 299442-43-6

A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 Get Quote
5MG 56 Get Quote
10MG 87 Get Quote
25MG 177 Get Quote
50MG 309 Get Quote
100MG 471 Get Quote
200MG 678 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    NKY80
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.
  • Description
    A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively; displays little to no activity for other AC isoforms (IC50>100 uM); blocks both BAPTA-AM-stimulated cAMP formation and renin release in primary cultures of juxtaglomerular cells.
  • Synonyms
    NKY 80;NKY-80
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Adenylate Cyclase
  • Recptor
    Adenylate Cyclase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    299442-43-6
  • Formula Weight
    229.24
  • Molecular Formula
    C12H11N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1C2=CN=C(N)N=C2CC(C3=CC=CO3)C1
  • Chemical Name
    2-amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Onda T, et al. J Biol Chem. 2001 Dec 21;276(51):47785-93.
2. Ortiz-Capisano MC, et al. Hypertension. 2007 Mar;49(3):618-24.
3. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
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