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CZEN-002

CAS No. 581-05-5

CZEN-002 ( α-Melanocyte-Stimulating Hormone (MSH) amide )

Catalog No. M21154 CAS No. 581-05-5

CZEN-002 is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CZEN-002
  • Note
    Research use only not for human use.
  • Brief Description
    CZEN-002 is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
  • Description
    CZEN-002 is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
  • Synonyms
    α-Melanocyte-Stimulating Hormone (MSH) amide
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Adenylate Cyclase
  • Recptor
    Adenylyl cyclase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    581-05-5
  • Formula Weight
    1664.88
  • Molecular Formula
    C77H109N21O19S
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (30.03 mM; Need ultrasonic)
  • SMILES
    OC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc2cncn2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc5cnc4ccccc45)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N6CCC[C@H]6C(=O)N[C@H](C(N)=O)C(C)C
  • Chemical Name
    (4S7S10S13S16S22S)-7-((1H-imidazol-4-yl)methyl)-16-((1H-indol-3-yl)methyl)-26-amino-22-((S)-2-(((S)-1-amino-3-methyl-1-oxobutan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-10-benzyl-13-(3-guanidinopropyl)-4-((2S5S8S11S)-8-(4-hydroxybenzyl)-511-bis(hydroxymethyl)-2-(2-(methylthio)ethyl)-471013-tetraoxo-36912-tetraazatetradecanamido)-5811141720-hexaoxo-6912151821-hexaazahexacosanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lu X Y Barsh G S Akil H et al. Interaction between α-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses[J]. Journal of Neuroscience the Official Journal of the Society for Neuroscience 2003 23(21):7863.
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