Cart
sales@molnova.com
SRTCX1002
CAS No. 1203479-63-3
SRTCX1002 ( SRTCX-1002 )
Catalog No. M10742 CAS No. 1203479-63-3
SRTCX1002 (SRTCX-1002) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.4 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSRTCX1002
-
NoteResearch use only, not for human use.
-
Brief DescriptionSRTCX1002 (SRTCX-1002) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.4 uM.
-
DescriptionSRTCX1002 (SRTCX-1002) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.4 uM, enhances deacetylation of cellular p65 protein with IC50 of 0.84 uM in cellular p65 acetylation assay; suppresses TNFα-induced NF-κB transcriptional activation and reduction of LPS-stimulated TNFα secretion in a SIRT1-dependent manner.
-
SynonymsSRTCX-1002
-
PathwayChromatin/Epigenetic
-
TargetSirtuin
-
RecptorSirtuin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1203479-63-3
-
Formula Weight405.48
-
Molecular FormulaC21H19N5O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=C2NC(C3=CC=CC(N4CCOCC4)=C3)=NC2=CC=C1)NC5=NC=CS5
-
Chemical Name2-[3-(4-Morpholinyl)phenyl]-N-2-thiazolyl-1H-benzimidazole-7-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Yang H, et al. PLoS One. 2012;7(9):e46364.
2. Kim SY, et al. PLoS One. 2015 Jul 15;10(7):e0133448.
2. Kim SY, et al. PLoS One. 2015 Jul 15;10(7):e0133448.
molnova catalog
related products
-
Fisetin
Extracted from Rhus succedanea L;Store the product in sealed, cool and dry condition.
-
Nicotinamide ribosid...
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
-
Magnoflorine iodide
Magnoflorine has anti-inflammatory activity, it can inhibit inflammations.
