SIRT-IN-2

CAS No. 1431411-66-3

SIRT-IN-2 ( —— )

Catalog No. M23596 CAS No. 1431411-66-3

SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 260 In Stock
10MG 430 In Stock
25MG 710 In Stock
50MG 972 In Stock
100MG 1332 In Stock
500MG 2673 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SIRT-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).
  • Description
    SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    SIRT1;SIRT2;SIRT3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1431411-66-3
  • Formula Weight
    383.5
  • Molecular Formula
    C15H21N5O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL?(151.24 mM;?Need ultrasonic)
  • SMILES
    CS(NCCC(CC1)CCN1c1ncnc2c1sc(C(N)=O)c2)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Disch JS, et al. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79.
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