SIRT-IN-2

CAS No. 1431411-66-3

SIRT-IN-2 ( —— )

Catalog No. M23596 CAS No. 1431411-66-3

SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 260 In Stock
10MG 430 In Stock
25MG 710 In Stock
50MG 972 In Stock
100MG 1332 In Stock
500MG 2673 In Stock
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Biological Information

  • Product Name
    SIRT-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).
  • Description
    SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    SIRT1;SIRT2;SIRT3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1431411-66-3
  • Formula Weight
    383.5
  • Molecular Formula
    C15H21N5O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL?(151.24 mM;?Need ultrasonic)
  • SMILES
    CS(NCCC(CC1)CCN1c1ncnc2c1sc(C(N)=O)c2)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Disch JS, et al. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79.
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