SPOP-IN-6lc( —— )

Catalog No. M36313 CAS No. 2136270-56-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

SPOP-IN-6lc
Note

Research use only, not for human use.
Brief Description

SPOP-IN-6lc is a potent SPOP inhibitor with multiple roles in cancer, oncostatic in a variety of tumors, but functions as an oncogene in renal cancer.SPOP-IN-6lc can be used to study cell signaling and apoptosis.
Description

SPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis
Research Area

——
Indication

——

CAS Number

2136270-56-7
Formula Weight

505.64
Molecular Formula

C26H31N7O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

C(CC1=CC=CS1)N2C3=C(C(=O)N4C(=N3)C(C)=CC=C4)C=C(C(NCCN5CCN(C)CC5)=O)C2=N
Chemical Name

——

1. Dong Z, et al. Structure-Activity Relationship of SPOP Inhibitors against Kidney Cancer. J Med Chem. 2020 May 14;63(9):4849-4866. ?

Calculator

molnova catalog