Cart
sales@molnova.com
Home - Products - Antibody Drug Conjugates (ADC) - ADCs Linker/Click Chemistry - SPDP

SPDP

CAS No. 68181-17-9

SPDP ( SPDP Crosslinker, SPDP Cross linker, SPDP Cross-linker, SPDP NHS ester )

Catalog No. M15603 CAS No. 68181-17-9

A heterobifunctional crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 31 In Stock
10MG 45 In Stock
25MG 67 In Stock
50MG 120 In Stock
100MG 203 In Stock
200MG 356 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SPDP
  • Note
    Research use only, not for human use.
  • Brief Description
    A heterobifunctional crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.
  • Description
    A heterobifunctional crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.
  • Synonyms
    SPDP Crosslinker, SPDP Cross linker, SPDP Cross-linker, SPDP NHS ester
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    68181-17-9
  • Formula Weight
    312.36
  • Molecular Formula
    C12H12N2O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2
  • Chemical Name
    Propanoic acid, 3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Woo BH, et al. Arch Pharm Res. 1994 Dec;17(6):452-7.
2. Lobedanz S, et al. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4612-7.
3. Ma G, et al. Int J Nanomedicine. 2013;8:1029-35.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Amino-PEG8-Boc

    Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

  • DBCO acid 4

    DBCO acid 4 is a Click Chemistry intermidate used for antibody-drug conjugates.

  • DBCO acid 2

    DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates.

Sign In Join Free