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Home - Products - Antibody Drug Conjugates (ADC) - ADCs Linker/Click Chemistry - Fmoc-Val-Cit-PAB

Fmoc-Val-Cit-PAB

CAS No. 159858-22-7

Fmoc-Val-Cit-PAB ( Fmoc-Val-Cit-PAB-OH; ADC linker )

Catalog No. M12292 CAS No. 159858-22-7

Fmoc-Val-Cit-PAB is a peptide prodrug linker for antibody-drug conjugates (ADCs), a cleavable ADC linker for antibody-drug conjugate.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fmoc-Val-Cit-PAB
  • Note
    Research use only, not for human use.
  • Brief Description
    Fmoc-Val-Cit-PAB is a peptide prodrug linker for antibody-drug conjugates (ADCs), a cleavable ADC linker for antibody-drug conjugate.
  • Description
    Fmoc-Val-Cit-PAB is a peptide prodrug linker for antibody-drug conjugates (ADCs), a cleavable ADC linker for antibody-drug conjugate.
  • Synonyms
    Fmoc-Val-Cit-PAB-OH; ADC linker
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADCinker;Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    159858-22-7
  • Formula Weight
    601.69
  • Molecular Formula
    C33H39N5O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 123.75 mg/mL
  • SMILES
    O=C(N)NCCC[C@H](NC([C@H](C(C)C)NC(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)=O)=O)C(NC4=CC=C(CO)C=C4)=O
  • Chemical Name
    L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Doronina SO, et al. Nat Biotechnol. 2003 Jul;21(7):778-84.
2. Doronina SO, et al. Bioconjug Chem. 2008 Oct;19(10):1960-3.
3. Beckley NS, et al. Bioconjug Chem. 2013 Oct 16;24(10):1674-83.
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