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SNDX-5613
CAS No. 2169919-21-3
SNDX-5613 ( —— )
Catalog No. M23982 CAS No. 2169919-21-3
SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | In Stock |
|
| 5MG | 147 | In Stock |
|
| 10MG | 259 | In Stock |
|
| 25MG | 514 | In Stock |
|
| 50MG | 737 | In Stock |
|
| 100MG | 1017 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSNDX-5613
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NoteResearch use only, not for human use.
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Brief DescriptionSNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM).
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DescriptionSNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorMenin-MLL
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Research Area——
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Indication——
Chemical Information
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CAS Number2169919-21-3
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Formula Weight630.8
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Molecular FormulaC32H47FN6O4S
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Purity>98% (HPLC)
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SolubilityDMSO:41.67 mg/mL (66.06 mM; Need ultrasonic)
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SMILESO=C(C1=CC(F)=CC=C1OC2=CN=CN=C2N3CC4(C3)CCN(CC4)C[C@H]5CC[C@@H](CC5)NS(=O)(CC)=O)N(C(C)C)CC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.A drug, SNDX-5613, to treat acute leukemia with a KMT2A translocation or an NPM1 mutation that has come back (relapsed) or has not gotten better with treatment (refractory).
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