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Thiomyristoyl
CAS No. 1429749-41-6
Thiomyristoyl ( Thiomyristoyl )
Catalog No. M11816 CAS No. 1429749-41-6
Thiomyristoyl is a highly selective and potent SIRT2 inhibitor with IC50 of 28 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 63 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 113 | In Stock |
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| 25MG | 215 | In Stock |
|
| 50MG | 361 | In Stock |
|
| 100MG | 537 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameThiomyristoyl
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NoteResearch use only, not for human use.
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Brief DescriptionThiomyristoyl is a highly selective and potent SIRT2 inhibitor with IC50 of 28 nM.
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DescriptionThiomyristoyl is a highly selective and potent SIRT2 inhibitor with IC50 of 28 nM, displays no significant activity against SIRT1/3/5/6/7 (Ic50>100 uM); promotes c-Myc ubiquitination and degradation, exhibits broad anticancer effect in various human cancer cells while having limited effects on non-cancerous cells; demonstrates in vivo effect in mouse models of breast cancer.
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SynonymsThiomyristoyl
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSIRT1;SIRT2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1429749-41-6
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Formula Weight581.85
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Molecular FormulaC34H51N3O3S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 32 mg/mL
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SMILESO=C(OCC1=CC=CC=C1)N[C@@H](CCCCNC(CCCCCCCCCCCCC)=S)C(NC2=CC=CC=C2)=O
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Chemical NameCarbamic acid, N-[(1S)-1-[(phenylamino)carbonyl]-5-[(1-thioxotetradecyl)amino]pentyl]-, phenylmethyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Teng YB, et al. Sci Rep. 2015 Feb 23;5:8529.
2. Jing H, et al. Cancer Cell. 2016 Mar 14;29(3):297-310.
3. Wang Y, et al. Cell Chem Biol. 2017 Mar 16;24(3):339-345.
2. Jing H, et al. Cancer Cell. 2016 Mar 14;29(3):297-310.
3. Wang Y, et al. Cell Chem Biol. 2017 Mar 16;24(3):339-345.
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