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Home - Products - Chromatin/Epigenetic - Epigenetic Reader Domain - SGC-SMARCA-BRDVIII

SGC-SMARCA-BRDVIII

CAS No. 1997319-84-2

SGC-SMARCA-BRDVIII ( —— )

Catalog No. M28766 CAS No. 1997319-84-2

SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 222 Get Quote
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Biological Information

  • Product Name
    SGC-SMARCA-BRDVIII
  • Note
    Research use only, not for human use.
  • Brief Description
    SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.
  • Description
    SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.(In Vitro):SGC-SMARCA-BRDVIII blocks adipogenesis in 3T3-L1 murine fibroblasts.
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    SCP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1997319-84-2
  • Formula Weight
    371.4
  • Molecular Formula
    C19H25N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)OC(N(CC1)CCN1c1c(N)nnc(-c(cccc2)c2O)c1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Medellin B, et al. Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells. J Med Chem. 2022;65(1):507-519.
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