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SGC-707
CAS No. 1687736-54-4
SGC-707 ( SGC 707;SGC707 )
Catalog No. M12575 CAS No. 1687736-54-4
SGC-707 is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM; Kd=53 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 53 | In Stock |
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| 25MG | 88 | In Stock |
|
| 50MG | 176 | In Stock |
|
| 100MG | 311 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSGC-707
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NoteResearch use only, not for human use.
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Brief DescriptionSGC-707 is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM; Kd=53 nM).
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DescriptionSGC-707 is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM; Kd=53 nM); shows outstanding selectivity against 31 other methyltransferases and more than 250 non-epigenetic targets; active in cells, also bioavailable and suitable for animal studies.
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SynonymsSGC 707;SGC707
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorPRMT3
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number1687736-54-4
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Formula Weight298.34
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Molecular FormulaC16H18N4O2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NCC(N1CCCC1)=O)NC2=CC3=C(C=NC=C3)C=C2
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Chemical NameUrea, N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kaniskan HU, et al. Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70.
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