Cart
sales@molnova.com
Home - Products - Microbiology/Virology - Enterovirus - SG85

SG85

CAS No. 1575662-24-6

SG85( SG 85 )

Catalog No. M12250 CAS No. 1575662-24-6

SG85 is a potent Enterovirus 3C protease inhibitor with EC50 of 180 nM against EV71 and 60 nM against human rhinovirus 14 in a live virus-cell-based assay.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SG85
  • Note
    Research use only, not for human use.
  • Brief Description
    SG85 is a potent Enterovirus 3C protease inhibitor with EC50 of 180 nM against EV71 and 60 nM against human rhinovirus 14 in a live virus-cell-based assay.
  • Description
    SG85 is a potent Enterovirus 3C protease inhibitor with EC50 of 180 nM against EV71 and 60 nM against human rhinovirus 14 in a live virus-cell-based assay; effectively inhibits the in vitro replication of 14 rhinoviruses representative of species A and B with mean EC50 of 40 nM, efficiently blocks rhinovirus replication and is not cross-resistant with rupintrivir.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SG 85
  • Pathway
    Microbiology/Virology
  • Target
    Enterovirus
  • Recptor
    Enterovirus
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1575662-24-6
  • Formula Weight
    650.773
  • Molecular Formula
    C35H46N4O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ethyl (5S,8S,11S,E)-8-benzyl-5-(tert-butoxymethyl)-3,6,9-trioxo-11-(((S)-2-oxopyrrolidin-3-yl)methyl)-1-phenyl-2-oxa-4,7,10-triazatetradec-12-en-14-oate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tijsma A, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. 2. Tan J, et al. J Virol. 2013 Apr;87(8):4339-51. 3. Lacroix C, et al. Antimicrob Agents Chemother. 2015 Sep;59(9):5814-8.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • TBZE-029

    TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication.

  • Pirlindole Mesylate

    Pirlindole is a novel potent inhibitor of Enteroviruse that targets Viral Protein 2C, inhibits EV-B and EV-D.

  • ICA135

    ICA135 (ICA-135, ICA 135) is a broad-spectrum inhibitor against human enteroviruses that inhibits Coxsackievirus A10 (CV-A10) replication in RD cells with IC50 of 1.446 uM.

Sign In Join Free