SF5

CAS No. 34634-22-5

SF5 ( SF-5; SF 5; 2,2-Diphenylethylisothiocyanate )

Catalog No. M27794 CAS No. 34634-22-5

SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 393 Get Quote
10MG 581 Get Quote
25MG 888 Get Quote
50MG 1242 Get Quote
100MG 1674 Get Quote
500MG 3348 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SF5
  • Note
    Research use only, not for human use.
  • Brief Description
    SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.
  • Description
    SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.(In Vitro):SF5 shows strong cell survival effect of kidney epithelial cells (93% at a concentration of 2.5 μM).
  • Synonyms
    SF-5; SF 5; 2,2-Diphenylethylisothiocyanate
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    ribonucleotide reductase(RR);Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34634-22-5
  • Formula Weight
    239.3
  • Molecular Formula
    C15H13NS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    S=C=NCC(c1ccccc1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Larsen IK, et al. Caracemide, a site-specific irreversible inhibitor of protein R1 of Escherichia coli ribonucleotide reductase. J Biol Chem. 1992 Jun 25;267(18):12627-31.
molnova catalog
related products
  • JPH203

    JPH203 (KYT-0353)is a potent, selective L-type amino acid transporter 1 (LAT1, SLC7A5) inhibitor with IC50 of 60 nM (leucine uptake inhibition).

  • Ecdysone

    Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death.

  • Pyrazoloacridine

    Pyrazoloacridine is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.