Rubitecan
CAS No. 91421-42-0
Rubitecan ( RFS 2000;9-Nitrocamptothecin )
Catalog No. M20618 CAS No. 91421-42-0
Rubitecan is a DNA topoisomerase I inhibitor.?It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
10MG | 63 | In Stock |
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50MG | 151 | In Stock |
|
100MG | 227 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameRubitecan
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NoteResearch use only not for human use.
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Brief DescriptionRubitecan is a DNA topoisomerase I inhibitor.?It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties.
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DescriptionRubitecan is a DNA topoisomerase I inhibitor.?It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties.
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SynonymsRFS 2000;9-Nitrocamptothecin
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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Recptortopoisomerase I
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Research AreaCancer
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IndicationTumors
Chemical Information
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CAS Number91421-42-0
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Formula Weight393.35
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Molecular FormulaC20H15N3O6
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (317.78 mM)
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SMILESCC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc([N+]([O-])=O)c4cc3Cn1c2=O
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Chemical Name(S)-4-ethyl-4-hydroxy-10-nitro-1H-pyrano[3'4':67]indolizino[12-b]quinoline-314(4H12H)-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sands H Mishra A Stoeckler J D et al. Preclinical activity of an i.v. formulation of rubitecan in IDD-P against human solid tumor xenografts[J]. Anti-Cancer Drugs 2002 13(9):965-975.
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