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Risdiplam
CAS No. 1825352-65-5
Risdiplam( RG7916 | RG-7916 | RO7034067 )
Catalog No. M12817 CAS No. 1825352-65-5
Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active?SMN2 splicing modifier for treatment of?spinal muscular atrophy (SMA).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 73 | In Stock |
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| 5MG | 116 | In Stock |
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| 10MG | 190 | In Stock |
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| 25MG | 338 | In Stock |
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| 50MG | 503 | In Stock |
|
| 100MG | 707 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRisdiplam
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NoteResearch use only, not for human use.
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Brief DescriptionRisdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active?SMN2 splicing modifier for treatment of?spinal muscular atrophy (SMA).
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DescriptionRisdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active?SMN2 splicing modifier for treatment of?spinal muscular atrophy (SMA); RG7916 is undergoing clinical trials across the spectrum of spinal muscular atrophy, where it has shown promising early results.Spinal Muscular Atrophy (SMA) Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsRG7916 | RG-7916 | RO7034067
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PathwayOthers
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TargetSMN2
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RecptorSMN2
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Research AreaNeurological Disease
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IndicationSpinal Muscular Atrophy(SMA)
Chemical Information
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CAS Number1825352-65-5
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Formula Weight401.474
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Molecular FormulaC18H29N3O3
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Purity>98% (HPLC)
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SolubilityEthanol : < 1 mg/mL; DMSO : < 1 mg/mL
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SMILESO=C1C=C(C2=NN3C(C(C)=C2)=NC(C)=C3)N=C4N1C=C(N(C5)CCNC65CC6)C=C4
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Chemical Name7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mammas IN, et al. Exp Ther Med. 2018 Apr;15(4):3673-3679.
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