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RUC-4
CAS No. 1448313-27-6
RUC-4 ( RUC4;RUC 4 )
Catalog No. M11916 CAS No. 1448313-27-6
A potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 963 | Get Quote |
|
| 50MG | 1962 | Get Quote |
|
| 100MG | 2520 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRUC-4
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.
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DescriptionA potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.
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SynonymsRUC4;RUC 4
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIntegrin
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Research Area——
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Indication——
Chemical Information
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CAS Number1448313-27-6
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Formula Weight386.43
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Molecular FormulaC16H18N8O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=NC=CC(C(S2)=NN(C2=NC(N3CCNCC3)=C4)C4=O)=C1)CN
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Chemical Name2-amino-N-(5-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-3-yl)acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Miller LM, et al. J Med Chem. 2017 Apr 27;60(8):3241-3251.
2. Jiang JK, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1148-53.
2. Jiang JK, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1148-53.
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