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RG7834

CAS No. 2072057-17-9

RG7834 ( RO 7020322 )

Catalog No. M23930 CAS No. 2072057-17-9

RG7834 is a highly selective and orally bioavailable inhibitor of HBV(HBsAg and HBeAg and HBV DNA with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RG7834
  • Note
    Research use only, not for human use.
  • Brief Description
    RG7834 is a highly selective and orally bioavailable inhibitor of HBV(HBsAg and HBeAg and HBV DNA with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells).
  • Description
    RG7834 is a highly selective and orally bioavailable inhibitor of HBV(HBsAg and HBeAg and HBV DNA with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells).
  • Synonyms
    RO 7020322
  • Pathway
    Microbiology/Virology
  • Target
    HBV
  • Recptor
    HBeAg;HBsAg;HBV DNA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2072057-17-9
  • Formula Weight
    401.5
  • Molecular Formula
    C22H27NO6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (311.37 mM; Need ultrasonic)
  • SMILES
    CC(C)[C@@H]1CC2=CC(=C(C=C2C3=CC(=O)C(=CN13)C(=O)O)OC)OCCCOC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Han X, et al. Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action. J Med Chem. 2018 Oct 4.
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