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RO6889678

CAS No. 1578153-27-1

RO6889678( RO 6889678 )

Catalog No. M12255 CAS No. 1578153-27-1

RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RO6889678
  • Note
    Research use only, not for human use.
  • Brief Description
    RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.
  • Description
    RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.HBV InfectionPhase 1 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    RO 6889678
  • Pathway
    Microbiology/Virology
  • Target
    HBV
  • Recptor
    HBV
  • Research Area
    Infection
  • Indication
    HBV Infection

Chemical Information

  • CAS Number
    1578153-27-1
  • Formula Weight
    494.922
  • Molecular Formula
    C21H20ClFN4O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C([C@H]1N(CC2=C(C(OC)=O)[C@H](C3=CC=C(F)C=C3Cl)N=C(C4=NC=CS4)N2)CCOC1)O
  • Chemical Name
    (S)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholine-3-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kratochwil NA, et al. J Pharmacol Exp Ther. 2018 Feb 16. pii: jpet.117.245712.
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